Hydrodynamics of multicomponent vesicles

A phase-field approach

verfasst von
Zuowei Wen, Navid Valizadeh, Timon Rabczuk, Xiaoying Zhuang
Abstract

In this paper, we introduce a thermodynamically-consistent phase-field model to investigate the hydrodynamics of inextensible multicomponent vesicles in various fluid flows with inertial forces. Our model couples the fluid field, surface concentration field representing chemical species on the membrane, and vesicle dynamics, while enforcing global area and volume constraints through a Lagrange multiplier method. Specifically, we employ full Navier–Stokes equations for the fluid field, the Cahn–Hilliard equations for the species concentration on the membrane, a nonlinear advection–diffusion equation to describe the evolution of the vesicle membrane, and an additional equation to enforce local inextensibility. We utilize a residual-based variational multiscale method for the Navier–Stokes equations and a standard Galerkin finite element framework for the remaining equations. The PDEs are solved using an implicit, monolithic scheme based on the generalized-α time integration method. We extend previous models for homogeneous vesicles (Aland et al., 2014; Valizadeh and Rabczuk, 2022) to multicomponent vesicles, introducing Cahn–Hilliard equations while maintaining thermodynamic consistency. Additionally, we employ isogeometric analysis (IGA) for higher accuracy. We present a variety of two-dimensional numerical examples, including multicomponent vesicles in shear flow and Poiseuille flow with and without obstructions, using the resistive immersed surface method to handle obstructions. Furthermore, we provide three-dimensional simulations of multicomponent vesicles in Poiseuille flow.

Organisationseinheit(en)
Institut für Photonik
Externe Organisation(en)
Bauhaus-Universität Weimar
Typ
Artikel
Journal
Computer Methods in Applied Mechanics and Engineering
Band
432
Anzahl der Seiten
29
ISSN
0045-7825
Publikationsdatum
01.12.2024
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Numerische Mechanik, Werkstoffmechanik, Maschinenbau, Allgemeine Physik und Astronomie, Angewandte Informatik
Elektronische Version(en)
https://doi.org/10.1016/j.cma.2024.117390 (Zugang: Geschlossen)
 

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